What is PlurvelRX
PlurvelRX is an advanced dual-phase bioregenerative skin treatment designed to repair, hydrate, and rejuvenate aging, compromised, or depleted skin. This protocol utilizes Polynucleotide (PN) therapy in combination with controlled microchanneling and Jet Plasma technology to stimulate cellular repair, improve skin quality, and restore long-term skin health.
Polynucleotides are bio-regenerative DNA fragments that support tissue repair, enhance hydration, strengthen the skin barrier, and promote collagen remodeling. PlurvelRX delivers progressive regeneration without aggressive trauma, making it ideal for clients seeking visible rejuvenation with minimal downtime.
What does it treat
• Skin laxity and crepey texture
• Dehydrated or compromised skin
• Fine lines and early aging
• Dull, fatigued, or stressed skin
• Loss of skin density and elasticity
• Impaired skin barrier function
• Post-procedure or post-inflammatory skin
• Early collagen depletion
Our Technique
Every RX Skin Renewal Collection treatment begins with professional dermaplaning to remove dead skin cells and vellus hair, creating a smooth, clean canvas for optimal penetration of active ingredients and enhanced results.
PlurvelRX is performed as a two-treatment regenerative protocol, with both treatments utilizing the Plurvel PN Booster and strategically timed to maximize skin repair and collagen regeneration.
Treatment 1 – Initial Regeneration (0.25 mm)
• Professional dermaplaning and skin preparation
• Jet Plasma technology to tighten, brighten, and stimulate cellular activity
• Plurvel PN Booster infused using gentle microchanneling at 0.25 mm
• Focuses on hydration, barrier repair, inflammation reduction, and cellular signaling
This first treatment prepares the skin and initiates regeneration at a superficial level.
Treatment 2 – Advanced Regeneration
(Scheduled ~3 Weeks Later)
• Performed approximately three weeks after Treatment 1
• Skin is reassessed based on healing response
• Plurvel PN Booster is infused again, this time using deeper microchanneling at 0.30–0.50 mm
• Targets collagen stimulation, skin density, elasticity, and long-term rejuvenation
This staged approach allows the skin to heal, adapt, and respond optimally before deeper regenerative stimulation is performed.
What to Expect
• Treatment time: approximately 75–90 minutes
• Mild redness, warmth, or tightness for 24–48 hours
• Light dryness or flaking may occur during healing
• Minimal downtime compared to traditional microneedling
• Progressive improvement over several weeks
• Best results achieved as a two-treatment series
Aftercare
Following PlurvelRX, proper aftercare is essential for optimal regeneration:
• Do not touch, rub, or pick at the treated area for 48 hours
• Avoid makeup for 24–48 hours
• Use only gentle cleanser and hydrating products recommended by your provider for 72 hours
• Avoid active skincare (retinoids, AHAs, BHAs, benzoyl peroxide, Vitamin C) for 7 days
• No saunas, hot tubs, sweating, or strenuous exercise for 48 hours
• Avoid direct sun exposure and tanning beds for 7–10 days
• Apply medical-grade SPF daily once healing begins
• Avoid waxing, chemical peels, or laser treatments in the treated area for 2 weeks
Contraindications
PlurvelRX may not be suitable for clients who:
• Are pregnant or breastfeeding
• Have active skin infections, open wounds, or inflamed acne in the treatment area
• Have uncontrolled autoimmune or inflammatory skin conditions
• Are currently undergoing chemotherapy or immunosuppressive therapy
• Have bleeding disorders or impaired wound healing
• Have a history of keloid scarring
• Have active herpes simplex lesions in the treatment area
A full consultation and medical history review are required prior to treatment.
Disclaimer
PlurvelRX is a cosmetic, non-surgical skin rejuvenation service performed under physician delegation in Wisconsin. Results vary based on skin condition, lifestyle, and number of treatments. This service is cosmetic only and does not diagnose, treat, or cure medical conditions.
Book Your Treatment
Experience advanced skin regeneration focused on repair, hydration, and long-term skin health. PlurvelRX is ideal for clients seeking visible rejuvenation without aggressive downtime.
